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Even though major, lifestyle-threatening, or deadly respiratory despair can occur at any time for the duration of using DILAUDID INJECTION, the risk is finest through the initiation of therapy or adhering to a dosage boost.

The pharmacokinetics of hydromorphone are afflicted by renal impairment. Start out individuals with renal impairment on a person-fourth to one-fifty percent the usual beginning dose with regards to the degree of impairment.

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DILAUDID INJECTION consists of sodium metabisulfite, a sulfite that could trigger allergic-type reactions like anaphylactic indicators and everyday living-threatening or fewer critical asthmatic episodes in particular prone people.

You shouldn’t acquire hydromorphone or morphine inside of 14 days of getting a monoamine oxidase inhibitor (MAOI).

Propulsive peristaltic waves within the colon are decreased, though tone could possibly be greater to The purpose of spasm, causing constipation. Other opioid-induced outcomes may contain a reduction in biliary and pancreatic secretions, spasm of sphincter of Oddi, and transient elevations in serum amylase.

Numerous brings about, from anxiety on the flu to specified Serious ailments can cause human body aches. Study what might be creating your symptoms.

Warn people never to drive or function perilous machinery Except They may be tolerant to the effects of DILAUDID INJECTION and understand how they may react towards the medication.

Hydromorphone and morphine are narcotics that function in the identical way, so their drug interactions may also be very similar.

irregular vision, like adjustments in color eyesight (like using a blue color tinge) and blurred vision

The causal position of opioids during the medical syndrome of hypogonadism is unidentified as the several clinical, physical, lifestyle, and psychological stressors that will influence gonadal hormone levels haven't been sufficiently controlled for in studies executed up to now read more [see ADVERSE REACTIONS].

Reserve concomitant prescribing of DILAUDID Injection and benzodiazepines or other CNS depressants to be used in sufferers for whom substitute therapy choices are insufficient.

You should also speak about your safety For those who have a heritage of drug abuse or habit. These medications might be addictive and raise your danger of overdose and Dying.